Diagnosis of Acute Pulmonary Histoplasmosis by Antigen Detection
نویسندگان
چکیده
منابع مشابه
Diagnosis of acute pulmonary histoplasmosis by antigen detection.
BACKGROUND Antigen detection, which has proven useful in diagnosis of disseminated histoplasmosis, has not been studied in acute pulmonary histoplasmosis (APH). Because treatment is indicated in most patients with moderately severe or severe APH, antigen detection for rapid diagnosis could be helpful. METHODS Histoplasma antigen detection was evaluated in 130 patients with APH. RESULTS Anti...
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BACKGROUND Acute pulmonary histoplasmosis can be severe, especially following heavy inoculum exposure. Rapid diagnosis is critical and often possible by detection of antigen, but this test may be falsely negative in 17% of such cases. Antibody detection by enzyme immunoassay (EIA) may increase sensitivity and permit the measurement of immunoglobulin M (IgM) and immunoglobulin G (IgG) classes of...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2009
ISSN: 1058-4838,1537-6591
DOI: 10.1086/648421